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KMID : 0545120120220040567
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Journal of Microbiology and Biotechnology
2012 Volume.22 No. 4 p.567 ~ p.570
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In Vitro Activities of Antimicrobials Against Brucella abortus Isolates from Cattle in Korea During 1998-2006
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Heo Eun-Jeong
Kang Sung-Il
Kim Jong-Wan
Her Moon
Cho Dong-hee
Cho Yun-Sang
Hwang In-Yeong
Moon Jin-san
Wee Sung-Hwan
Jung Suk-Chan
Nam Hyang-Mi
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Abstract
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In vitro activities of 13 antibiotics were assessed against 85 Brucella abortus isolates from naturally infected cattle in the Republic of Korea during 1998-2006, using broth microdilution test. Tetracyclines showed the most excellent activity against B. abortus, displaying MIC values of 0.5 μg/ml or below. In particular, minocycline showed the lowest MIC50/90 values (0.125/0.125 μg/ml) in this study. Among four fluoroquinolones tested, ciprofloxacin (MIC50/90, 0.5/1 μg/ml) and norfloxacin (MIC50/90, 8/8 μg/ml) had the most and the least activities, respectively. Gentamicin (MIC50/90, 1/1 μg/ml) was more effective than streptomycin, erythromycin, rifampin, and chloramphenicol (MIC50/90, 2/2 μg/ml).
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KEYWORD
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Antimicrobial susceptibility, Brucella abortus, Cattle
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